Vioxx, a nonsteroidal anti-inflammatory drug (NSAID) relieves chronic pain, osteoarthritis related pain and menstrual cramps. The active ingredient in Vioxx is called Rofecoxib. Recent studies have shown that Vioxx increases the risk for heart attack and stroke when taken for at least 18 months.

Rofecoxib, the active ingredient in Vioxx, works by blocking the enzyme responsible for making prostaglandins, which are the chemicals that promote inflammation and its resulting pain, fever, swelling and tenderness. Vioxx differs from other nonsteroidal anti-inflammatory drug (NSAID) since it causes less irritation and ulceration of the stomach and intestine during short-term treatment. It is available in tablet form with 12.5 mg, 25 mg, and 50mg. doses, along with Oral Suspension coming in 12.5 mg/5 ml and 25mg/5ml. doses respectfully.

Vioxx should not be taken by those who are allergic to Aspirin or NSAID drugs. It is advised to contact your doctor before taking Vioxx if you smoke or drink alcohol, or if you have one of the following conditions: ulcer or stomach bleeding, liver disease, kidney disease, asthma, fluid retention, high blood pressure, heart disease, congestive heart failure, or blood coagulation disorder. Children, and pregnant or breast-feeding women also should not take Vioxx.

Common side effects may include dizziness, mild fatigue or weakness, nausea, heartburn, water retention, and diarrhea. Recent studies have also shown that Vioxx increases the risk for heart attack and stroke when taken for at least 18 months. Vioxx may interact blood pressure medications, other anti-inflammatory drugs, lithium, methotrexate, rifampin, and anticoagulants. Drinking alcohol when taking Vioxx is also highly discouraged. If you are taking other drugs, it is also advised to contact your doctor before taking Vioxx.